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1

Eicosanoids in Inflammation: Biosynthesis, Pharmacology, and Therapeutic Frontiers

Khanapure, Subhash, Garvey, David, Janero, David, Gordon Letts, L.

Journal:

Current Topics in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 212 KB

english, 2007

2

The Total Synthesis of Tritiated and Deuterated 5-Oxo-ETE, a Novel Inflammatory Mediator

Khanapure, Subhash P., Shi, Xiao-Xin, Powell, William S., Rokach, Joshua

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 68 KB

english, 1998

3

A Facile One-Step Synthesis of Novel Polysubstituted Pyridines via the Tandem-Addition Rearrangement Hetaryne Reaction

R. Biehl, Edward, P. Khanapure, Subhash

Journal:

Year:

1990

Language:

english

File:

PDF, 299 KB

english, 1990

4

An improved stereospecific total synthesis of an aromatic c-ring testosterone analogue

Khanapure, Subhash P., Hazra, Braja G., Das, K. G.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1981

Language:

english

File:

PDF, 451 KB

english, 1981

5

Deblocking of dithioacetals and oxathioacetals using periodic acid under mild nonaqueous conditions

Xiao-Xin Shi, Subhash P. Khanapure, Joshua Rokach

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 225 KB

english, 1996

6

Crystal structure of 5,10-(diphenyl)-5,10-dihydrophenarsazine

Upali Siriwardane, Aziz Razzuk, Subhash P. Khanapure, Edward R. Biehl, Shirley S. C. Chu

Journal:

Journal of Heterocyclic Chemistry

Year:

1988

File:

PDF, 293 KB

1988

7

Synthesis of Morindaparvin A, an Antitumor Agent, and Related Anthraquinones

Khanapure, Subhash P., Biehl, Edward R.

Journal:

Journal of Natural Products

Year:

1989

Language:

english

File:

PDF, 225 KB

english, 1989

8

Efficient Synthesis of a Benzo[ b ]furan Building Block

Lee, Jaekyoo, Khanapure, Subhash P., Kim, Hwa-Ok, Rajur, Raj (S. B.), Li, Bing, Williams, John D., Pai, Ramdas, Peet, Norton P.

Journal:

Synthetic Communications

Year:

2010

Language:

english

File:

PDF, 241 KB

english, 2010

9

Total Synthesis of 17,17,18,18-d4-iPF2α-VI and Quantification of iPF2α-VI in Human Urine by Gas Chromatography/Mass Spectrometry

Mustafa Adiyaman, John A. Lawson, Subhash P. Khanapure, Garret A. FitzGerald, Joshua Rokach

Journal:

Analytical Biochemistry

Year:

1998

Language:

english

File:

PDF, 301 KB

english, 1998

10

Reaction of 4-bromo-1,2-dimethylbenzene with various nucleophiles via aryne reaction

Biehl, Edward R., Razzuk, Aziz, Jovanovic, Misa V., Khanapure, Subhash P.

Journal:

Journal of Organic Chemistry

Year:

1986

Language:

english

File:

PDF, 440 KB

english, 1986

11

Regioncontrolled formation of iodohy dnns and expoxides from Vic-diols

Mustafa Adiyaman, Subhash P. Khanapure, Seong Woo Hwang, Joshua Rokach

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 301 KB

english, 1995

12

The preparation of anthraquinones and anthracyclinones via the reaction of haloarenes and cyanophthalides under aryne-forming conditions

Khanapure, Subhash P., Reddy, R. Thimma, Biehl, Edward R.

Journal:

Journal of Organic Chemistry

Year:

1987

Language:

english

File:

PDF, 780 KB

english, 1987

13

Quantitative Analysis of 5-Oxo-6,8,11,14-eicosatetraenoic Acid by Electrospray Mass Spectrometry Using a Deuterium-Labeled Internal Standard

William S. Powell, Daniel Boismenu, Subhash P. Khanapure, Joshua Rokach

Journal:

Analytical Biochemistry

Year:

2001

Language:

english

File:

PDF, 66 KB

english, 2001

14

Hard acid and soft nucleophile systems. part 12. Regioselective functionalization of 1,3-dienes through the lewis acid mediated thienium cation diels-alder reaction

Kaoru Fuji, Subhash P. Khanapure, Manabu Node, Takeo Kawabata, Akichika ltoh, Yukio Masaki

Journal:

Year:

1990

Language:

english

File:

PDF, 545 KB

english, 1990

15

Use of highly reactive, versatile and air-stable palladium–phosphinous acid complex [(t-Bu)2P(OH)]2PdCl2 (POPd) as a catalyst for the optimized Suzuki–Miyaura cross-coupling of less reactive heteroaryl chlorides and arylboronic acids

Subhash P. Khanapure, David S. Garvey

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 267 KB

english, 2004

16

The synthesis of a 5-HETE photoaffinity ligand

Goutam Saha, Subhash P Khanapure, William S Powell, Joshua Rokach

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 179 KB

english, 2000

17

An efficient approach to the synthesis of LTB4 and ω-substituted LTB4 metabolites

Subhash P. Khanapure, Seongjin Kim, John F. Penrose, K.Frank Austen, William S. Powell, Joshua Rokach

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 160 KB

english, 2002

18

A comparison of the cyclooxygenase inhibitor-NO donors (CINOD), NMI-1182 and AZD3582, using in vitro biochemical and pharmacological methods

Delano V. Young, Edward D. Cochran, Vijay Dhawan, Richard A. Earl, James L. Ellis, David S. Garvey, David R. Janero, Subhash P. Khanapure, L. Gordon Letts, Terry L. Melim, Madhavi G. Murty, Matthew J.

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 464 KB

english, 2005

19

Synthesis and Structure−Activity Relationship of Novel, Highly Potent Metharyl and Methcycloalkyl Cyclooxygenase-2 (COX-2) Selective Inhibitors

Khanapure, Subhash P., Garvey, David S., Young, Delano V., Ezawa, Maiko, Earl, Richard A., Gaston, Rick D., Fang, Xinqin, Murty, Madhavi, Martino, Allison, Shumway, Matthew, Trocha, Mark, Marek, Przem

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 392 KB

english, 2003

20

Total Synthesis of a Potent Proinflammatory 5-Oxo-ETE and Its 6,7-Dihydro Biotransformation Product

Khanapure, Subhash P., Shi, Xiao-Xin, Powell, William S., Rokach, Joshua

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 102 KB

english, 1998

21

High-Pressure Liquid Chromatography of Oxo-Eicosanoids Derived from Arachidonic Acid

William S. Powell, Lei Wang, Subhash P. Khanapure, Sukumar Manna, Joshua Rokach

Journal:

Analytical Biochemistry

Year:

1997

Language:

english

File:

PDF, 170 KB

english, 1997

22

NMI-1182, a gastro-protective cyclo-oxygenase-inhibiting nitric oxide donor

James L. Ellis, Michael E. Augustyniak, Edward D. Cochran, Richard A. Earl, David S. Garvey, Laura J. Gordon, David R. Janero, Subhash P. Khanapure, L. Gordon Letts, Terry L. Melim, Madhavi G. Murty,

Journal:

Inflammopharmacology

Year:

2005

Language:

english

File:

PDF, 213 KB

english, 2005

23

Preparation of anthraquinones from 10-hydroxy-9-anthracenecarbonitriles obtained from a novel aryne annulation reaction

Bhawal, Baburao M., Khanapure, Subhash P., Zhang, Hongming, Biehl, Edward R.

Journal:

Journal of Organic Chemistry

Year:

1991

Language:

english

File:

PDF, 532 KB

english, 1991

24

IPF2α-I: An Index of Lipid Peroxidation in Humans

Domenico Pratico, Orla P. Barry, John A. Lawson, Mustafa Adiyaman, Seong-Woo Hwang, Subhash P. Khanapure, Luigi Iuliano, Joshua Rokach and Garret A. FitzGerald

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.06 MB

english, 1998

25

The Total Synthesis of 5-Oxo-12( S )-hydroxy-6( E ),8( Z ),10( E ),14( Z )-eicosatetraenoic Acid and Its 8,9- trans -Isomer and Their Identification in Human Platelets

Khanapure, Subhash P., Powell, William S., Rokach, Joshua

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 98 KB

english, 1998

26

Editorial [Hot Topic: Anti-Inflammatory Therapy (Guest Editor: Dr. Subhash P. Khanapure)]

Khanapure, Subhash

Journal:

Current Topics in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 20 KB

english, 2007

27

Total synthesis of a novel isoprostane IPF2α-I and its identification in biological fluids

Mustafa Adiyaman, John A. Lawson, Seong-Woo Hwang, Subhash P. Khanapure, Garret A. FitzGerald, Joshua Rokach

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 242 KB

english, 1996

28

Use of N-lithiated ethyl anthranilates as 1,4-dipole equivalents in 1,4-dipolearyne cycloaddition: A novel approach to the synthesis of acridones

Subhash P. Khanapure, Baburao M. Bhawal, Edward R. Biehl

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 220 KB

english, 1990

29

Total Synthesis of 8-epi-PGF2.alpha.. A Novel Strategy for the Synthesis of Isoprostanes

Hwang, Seong Woo, Adiyaman, Mustafa, Khanapure, Subhash, Schio, Laurent, Rokach, Joshua

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 284 KB

english, 1994

30

Synthesis of polycyclics via aryne arylation reactions

Biehl, Edward R., Khanapure, Subhash P.

Journal:

Accounts of Chemical Research

Year:

1989

Language:

english

File:

PDF, 793 KB

english, 1989

31

Investigation of the Reaction of 2-Bromo-1,4-dimethoxynaphthalene and 9-Bromophenanthrene with Nitriles Under Aryne-Forming Conditions

Hansen, Marcus, Khanapure, Subhash P., Fry, Michael, Swartling, Dan, Biehl, Edward R.

Journal:

Year:

1994

File:

PDF, 375 KB

1994

32

Preparation of 4-alkyl and 4-aryl derivatives of 6-(acetoxymethyl)isochroman-3-one

Khanapure, Subhash P., Biehl, Edward R.

Journal:

Journal of Organic Chemistry

Year:

1987

Language:

english

File:

PDF, 622 KB

english, 1987

33

ChemInform Abstract: The Total Synthesis of 5-Oxo-12(S)-hydroxy-6(E),8(Z),10(E),14(Z)-eicosatetraenoic Acid and Its 8,9-trans-Isomer and Their Identification in Human Platelets.

Subhash Khanapure, William S. Powell, Joshua Rokach

Journal:

Year:

1999

File:

PDF, 34 KB

1999

34

Synthesis and Reaction of 7-Bromo-2-(trifluoromethyl)-10-methylphenothiazine with Nitriles and Amines under Aryne-forming Conditions

R. Biehl, Edward, DePaul, Susan, P. Khanapure, Subhash, L. Self, Jennifer, Siriwardane, Upali, Taylor, Stephen, D. Tran, Long, A. Tschantz, Matt

Journal:

Year:

1990

Language:

english

File:

PDF, 301 KB

english, 1990

35

Biological Inactivation of 5-oxo-6,8,11,14-Eicosatetraenoic Acid by Human Platelets

Powell, William S., Gravel, Sylvie, Khanapure, Subhash P., Rokach, Joshua

Journal:

Year:

1999

File:

PDF, 247 KB

1999

36

The design and synthesis of a 5-HETE affinity chromatography ligand for 5-hydroxyeicosanoid dehydrogenase

Subhash P Khanapure, Goutam Saha, William S Powell, Joshua Rokach

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 162 KB

english, 2000

37

3-[4-(Methylsulfonyl)phenyl]-5-(trifluoromethyl)(2-pyridyl) Phenyl Ketone as a Potent and Orally Active Cyclooxygenase-2 Selective Inhibitor: Synthesis and Biological Evaluation

Khanapure, Subhash P., Augustyniak, Michael E., Earl, Richard A., Garvey, David S., Letts, L. Gordon, Martino, Allison M., Murty, Madhavi G., Schwalb, David J., Shumway, Matthew J., Trocha, Andrzej M.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 104 KB

english, 2005

38

Synthesis of 10,11-Dihydro-12-oxo-LTB 4 , a Key Biochemical Intermediate

Khanapure, Subhash P., Wang, Steven S., Powell, William S., Rokach, Joshua

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 423 KB

english, 1997

39

ChemInform Abstract: Isoprostanes: Chemistry and Biological Significance

Joshua Rokach, Subhash P. Khanapure, Seong-Woo Hwang, Mustafa Adiyaman, Zaher Elmir, John A. Lawson, Garret A. FitzGerald

Journal:

Year:

1999

File:

PDF, 25 KB

1999

40

A stereocontrolled synthesis of cis-3,4-diarylisochroman-1-ones through diastereoselective reaction of benzaldehydes and α-lithio-2-cyanodiarylmethane intermediates.

Lori Crenshaw, Subhash P. Khanapure, Upali Siriwardane, Edward R. Biehl

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 215 KB

english, 1988

41

Diels−Alder Approach to Isoprostanes. Total Synthesis of iPF 2α -V

Pudukulathan, Zubaidha, Manna, Sukumar, Hwang, Seong-Woo, Khanapure, Subhash P., Lawson, John A., FitzGerald, Garret A., Rokach, Joshua

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 538 KB

english, 1998

42

The Use of 1,4-Dipolar Aryne Cycloaddition Strategy in Anthracyclinone Synthesis: The Formal Synthesis of (±)-4-Demethoxydaunomycinone

Khanapure, Subhash P., Biehl, Edward R.

Journal:

Year:

1991

File:

PDF, 333 KB

1991

43

Synthesis of polysubstituted benzenes via the tandem addition-rearrangement aryne reaction of substituted 2-bromoanisoles and lithioarenenitriles

Khanapure, Subhash P., Crenshaw, Lori, Reddy, R. Thimma, Biehl, Edward

Journal:

Journal of Organic Chemistry

Year:

1988

Language:

english

File:

PDF, 615 KB

english, 1988

44

Synthesis and X-ray structure of cis-4b,9b-diphenyl-4b,5,9b,10-tetrahydroindeno[2,1-a]indene-5,10-dione

Bhawal, Baburao M., Desmukh, Abdul Rakeeb, Zhang, Hongming, Khanapure, Subhash P., Biehl, Edward R.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1991

Language:

english

File:

PDF, 181 KB

english, 1991

45

Synthesis of Poly(methylphenyl)acetonitriles by the Aryne Reaction

Waggenspack, John H., Tran, Long, Taylor, Stephen, Yeung, Lee K., Morgan, Matt, Deshmukh, A. Rakeeb, Khanapure, Subhash P., Biehl, Edward R.

Journal:

Year:

1992

File:

PDF, 312 KB

1992

46

Lewis acid mediated thienium cation diels-alder reaction: A new method for regio- and stereoselective functionalization of 1,3-dienes

Kaoru Fuji, Subhash P. Khanapure, Manabu Node, Takeo Kawabata, Akichika Ito

Journal:

Tetrahedron Letters

Year:

1985

Language:

english

File:

PDF, 189 KB

english, 1985

47

ChemInform Abstract: Efficient Synthesis of a Benzo[b]furan Building Block.

Jaekyoo Lee, Subhash P. Khanapure, Hwa-Ok Kim, Raj Rajur, Bing Li, John D. Williams, Ramdas Pai, Norton P. Peet

Journal:

Year:

2011

File:

PDF, 36 KB

2011

48

First total synthesis of isoprostane IPF2α-III

Mustafa Adiyaman, Hongwei Li, John A. Lawson, Seong-Woo Hwang, Subhash P. Khanapure, Garret A. FitzGerald, Joshua Rokach

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 249 KB

english, 1997

49

Preparation of novel 4-substituted 6-methoxy-, 6,7-dimethoxy-, and 6,7-(methylenedioxy)isochroman-3-ones. 2

Khanapure, Subhash P., Biehl, Edward R.

Journal:

Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 687 KB

english, 1990

50

Rapid, Low-Temperature Amidation of Ethyl Cyano-Acetate with Lithium Amides Derived from primary and Secondary Amines

Bhawal, Baburao M., Khanapure, Subhash P., Biehl, Edward R.

Journal:

Synthetic Communications

Year:

1990

Language:

english

File:

PDF, 318 KB

english, 1990

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